Key Takeaways
- OpenEvidence valuation: the AI search platform built for physicians is now valued at $15 billion after raising $250 million.
- Ad commitments: according to a person close to the company, advertising commitments reached $100 million in 2025.
- Ad revenue forecast: according to a person close to the company, OpenEvidence expects $400 million to $500 million in ad revenue by the end of 2026.
- OpenEvidence usage: nearly two-thirds of US doctors use the tool to make clinical decisions, according to Atlabyte.
OpenEvidence, the AI search platform built for physicians, now has a $15 billion valuation after raising $250 million, according to Cryptobriefing and Atlabyte, both published October 21, 2026. Cryptobriefing calls the climb fast for a company founded in 2022.
OpenEvidence advertising commitments and ad revenue forecast
According to a person close to the company, advertising commitments for 2025 reached $100 million, and the company expects $400 million to $500 million in ad revenue by the end of 2026. Atlabyte does not name that person.
Cryptobriefing gives the valuation history as $6 billion, then $12 billion, then $15 billion, so the valuation rose 2.5 times.
Atlabyte reports that the service earns money from advertising commitments made by pharmaceutical companies and other market players.
Why OpenEvidence's advertising model is drawing debate
Atlabyte says the advertising model and the accuracy of the tool are sparking debate. The platform scans medical journals and clinical guidelines to help doctors diagnose and treat patients, and its search relies on peer-reviewed sources.
The overlap is what makes the story matter: one product both guides clinical decisions and earns advertising money.
Daniel Nadler founded OpenEvidence in 2022 with a specific problem in mind: information overload. Medical research piles up faster than any working clinician can read it, according to Cryptobriefing. Atlabyte quotes Nadler telling the FT, "We're the first viral consumer internet app in healthcare." That is Nadler's own description of the product.
OpenEvidence usage among US doctors and physicians
Cryptobriefing says nearly two-thirds of the roughly 1 million US physicians use the tool to help guide diagnoses and treatment decisions. The company said US physicians sent more than 42 million queries over the past month. Cryptobriefing also reports that by mid-2025, OpenEvidence was seeing daily use across more than 10,000 healthcare facilities.
The usage figures show how widely the tool has spread among doctors. The reports do not describe how any individual treatment decision changes.
What the advertising and usage figures do not show
The advertising figures rest on a person close to the company, who is not named. The 42 million query figure is the company's own, and Atlabyte gives no date beyond the past month. Neither outlet links the advertising figures to the query count, so the reports do not show how usage and ad revenue relate. On total funding, Cryptobriefing says over $1 billion over 18 months, and Atlabyte says nearly $1 billion over the past 18 months. Both outlets report the $15 billion valuation, the $250 million amount and the nearly two-thirds usage share.
People Also Ask
What is OpenEvidence's valuation?
OpenEvidence is valued at $15 billion after raising $250 million, according to Cryptobriefing and Atlabyte. Both outlets report the same valuation and the same $250 million round, and both describe the company as Miami-based. Atlabyte describes the $250 million as the company's latest funding round.
How much ad revenue does OpenEvidence expect by the end of 2026?
According to a person close to the company, OpenEvidence expects $400 million to $500 million in ad revenue by the end of 2026. The same person said advertising commitments for 2025 reached $100 million. Atlabyte is the only one of the two outlets that reports these figures, and it does not name that person.
How many US doctors use OpenEvidence?
Nearly two-thirds of US doctors use OpenEvidence to make clinical decisions, according to Atlabyte. Cryptobriefing gives the same share of the roughly 1 million US physicians, and says they use OpenEvidence to help guide diagnoses and treatment decisions.
Who founded OpenEvidence?
Daniel Nadler founded OpenEvidence in 2022 in Miami with information overload in mind. Medical research piles up faster than any working clinician can read it, according to Cryptobriefing. Cryptobriefing and Atlabyte both name Nadler as the founder.
Sources: Cryptobriefing, Atlabyte.